According to Dan Michaels, DPM, "Many fungal infections, once they have developed, never resolve, and stay with the host for the rest of his or her life. If one occurs in the lung, the treatment itself is potentially debilitating, and the success rate low. This likewise is true for toenail infections. If not caught relatively early in this slow but inexorable process, it typically remains there, gradually, slowly worsening, for the remainder of their life."
"A healthy immune system prevents the more dire consequences of a tinea infection. But someone taking immune-suppressive drugs (such as an organ transplant recipient) or a person with diabetes is more likely to experience a secondary bacterial infection. And to a diabetic, these can be limb-threatening," says Dr. Michaels.